Sepsis DiagnosticsWhole blood samples Application Study: VYOO vs. Gold Standard Blood CultureThe purpose of this study, performed during product development, was to determine whether a molecular diagnostic approach using VYOO could offer a faster, more sensitive solution for detection of bacterial and fungal infections and antibiotic resistance as compared to conventional ‘gold standard' blood culture techniques. |
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Download VYOO Sepsis Study Reference literature
Truncated human cytidylate-phosphate-deoxyguanylate-binding protein for improved NAT-based detection of bacterial species in human samples.
Sachse S, Straube E, Lehmann M, Bauer M, Russwurm S, Schmidt KH., Journal of Clinical Microbiology, 2009
Paper on the specific enrichment of pathogen DNA incorporated in VYOO. Read the abstract and get the paper on pubmed online.
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New Approaches in Fungal DNA Preparation from Whole Blood and Subsequent Pathogen Detection Via Multiplex PCR
Schmitz RPH, Eck R, Lehmann M, Molecular Identification of Fungi, Springer, 2010
Multiplex PCR vs. Blood Culture: Towards a New Gold Standard in Sepsis Diagnostics
Sachse S, Lehmann M, Schmitz R, Reinhart K, Straube E
Performance of a PCR based assay for pathogen detection in critically ill patients
Bloos F, Kortgen A, Sachse S, Lehmann M, Straube E, Reinhart K, Bauer M
Clinical relevance of fungal DNAemia detected by multiplex PCR in septic patients
Kortgen A, Bloos F, Sachse S, Lehmann M, Straube E, Reinhart K, Bauer M
Applied Sepsis Diagnostics: Gold Standard Blood Culture vs. NAT-based Pathogen Detection
Sachse S, Lehmann M, Schmitz R, Russwurm S, Schmidt KH, Reinhart K, Straube EDetection of bacterial DNA in Platelet Concentrates (Apharese Products) and whole Blood using a uniqque Sample Preparation Tool and qPCR
Barz D, Sachse S, Lehmann M, Lorenzen T, Straube E: Poster at the DGTI Congress, Sep 18-22, Friedrichshafen, Germany